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ER stress and unfolded protein response in amyotrophic lateral sclerosis—a controversial role of protein disulphide isomerase

Accumulation of proteins in aberrant conformation occurs in many neurodegenerative diseases. Furthermore, dysfunctions in protein handling in endoplasmic reticulum (ER) and the following ER stress have been implicated in a vast number of diseases, such as amyotrophic lateral sclerosis (ALS). During...

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Detalles Bibliográficos
Autores principales:	Jaronen, Merja, Goldsteins, Gundars, Koistinaho, Jari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251436/ https://www.ncbi.nlm.nih.gov/pubmed/25520620 http://dx.doi.org/10.3389/fncel.2014.00402

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