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ANGIOTENSIN II INDUCED CARDIOVASCULAR LOAD REGULATES CARDIAC REMODELING AND RELATED GENE EXPRESSION IN LATE GESTATION FETAL SHEEP

BACKGROUND: Angiotensin II (ANG II) stimulates fetal heart growth, though little is known regarding changes in cardiomyocyte endowment or the molecular pathways mediating the response. We measured cardiomyocyte proliferation and morphology in ANG II treated fetal sheep and assessed transcriptional p...

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Detalles Bibliográficos
Autores principales: Norris, Andrew W., Bahr, Timothy M., Scholz, Thomas D., Peterson, Emily S., Volk, Ken A., Segar, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251591/
https://www.ncbi.nlm.nih.gov/pubmed/24614802
http://dx.doi.org/10.1038/pr.2014.37