Pharmacokinetics on a microscale: visualizing Cy5-labeled oligonucleotide release from poly(n-butylcyanoacrylate) nanocapsules in cells

For successful design of a nanoparticulate drug delivery system, the fate of the carrier and cargo need to be followed. In this work, we fluorescently labeled poly(n-butylcyanoacrylate) (PBCA) nanocapsules as a shell and separately an oligonucleotide (20 mer) as a payload. The nanocapsules were form...

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Detalles Bibliográficos
Autores principales: Tomcin, Stephanie, Baier, Grit, Landfester, Katharina, Mailänder, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251750/
https://www.ncbi.nlm.nih.gov/pubmed/25473285
http://dx.doi.org/10.2147/IJN.S70908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251750/
https://www.ncbi.nlm.nih.gov/pubmed/25473285
http://dx.doi.org/10.2147/IJN.S70908

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