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IL-1β and TNFα Promote Monocyte Viability through the Induction of GM-CSF Expression by Rheumatoid Arthritis Synovial Fibroblasts

Background. Macrophages and synovial fibroblasts (SF) are two major cells implicated in the pathogenesis of rheumatoid arthritis (RA). SF could be a source of cytokines and growth factors driving macrophages survival and activation. Here, we studied the effect of SF on monocyte viability and phenoty...

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Detalles Bibliográficos
Autores principales: Darrieutort-Laffite, Christelle, Boutet, Marie-Astrid, Chatelais, Mathias, Brion, Régis, Blanchard, Frédéric, Heymann, Dominique, Le Goff, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251793/
https://www.ncbi.nlm.nih.gov/pubmed/25484525
http://dx.doi.org/10.1155/2014/241840