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A case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy

BACKGROUND: Phacolytic glaucoma is induced by lens protein or macrophages that have leaked through a macroscopically intact anterior lens capsule. Here, we report a case of phacolytic glaucoma with anterior lens capsule disruptions visualized by scanning electron microscopy (SEM). CASE PRESENTATION:...

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Autores principales: Yoo, Woong-Sun, Kim, Byeong-Jae, Chung, In-Young, Seo, Seong-Wook, Yoo, Ji-Myong, Kim, Seong-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251857/
https://www.ncbi.nlm.nih.gov/pubmed/25407294
http://dx.doi.org/10.1186/1471-2415-14-133
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author Yoo, Woong-Sun
Kim, Byeong-Jae
Chung, In-Young
Seo, Seong-Wook
Yoo, Ji-Myong
Kim, Seong-Jae
author_facet Yoo, Woong-Sun
Kim, Byeong-Jae
Chung, In-Young
Seo, Seong-Wook
Yoo, Ji-Myong
Kim, Seong-Jae
author_sort Yoo, Woong-Sun
collection PubMed
description BACKGROUND: Phacolytic glaucoma is induced by lens protein or macrophages that have leaked through a macroscopically intact anterior lens capsule. Here, we report a case of phacolytic glaucoma with anterior lens capsule disruptions visualized by scanning electron microscopy (SEM). CASE PRESENTATION: A 71-year-old man was referred to our institute for increased intraocular pressure (IOP) in the right eye. Slit-lamp biomicroscopic examination revealed corneal edema, the presence of inflammatory cells and iridescent crystalline in the anterior chamber, and a hypermature cataract in the right eye. Despite treatment with topical glaucoma medication (0.15% brimonidine, 1% brinzolamide/0.5% timolol, and 0.03% bimatoprost) and systemic mannitol, his IOP remained uncontrolled. Light microscopy was used to examine the aqueous humor obtained via anterior chamber paracentesis and the anterior lens capsule obtained via intracapsular cataract extraction (ICCE), which revealed that the anterior lens capsule was intact. However, SEM revealed full-thickness disruptions in the anterior lens. CONCLUSION: This is the first reported case of phacolytic glaucoma with disruptions of the anterior lens capsule confirmed by SEM.
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spelling pubmed-42518572014-12-03 A case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy Yoo, Woong-Sun Kim, Byeong-Jae Chung, In-Young Seo, Seong-Wook Yoo, Ji-Myong Kim, Seong-Jae BMC Ophthalmol Case Report BACKGROUND: Phacolytic glaucoma is induced by lens protein or macrophages that have leaked through a macroscopically intact anterior lens capsule. Here, we report a case of phacolytic glaucoma with anterior lens capsule disruptions visualized by scanning electron microscopy (SEM). CASE PRESENTATION: A 71-year-old man was referred to our institute for increased intraocular pressure (IOP) in the right eye. Slit-lamp biomicroscopic examination revealed corneal edema, the presence of inflammatory cells and iridescent crystalline in the anterior chamber, and a hypermature cataract in the right eye. Despite treatment with topical glaucoma medication (0.15% brimonidine, 1% brinzolamide/0.5% timolol, and 0.03% bimatoprost) and systemic mannitol, his IOP remained uncontrolled. Light microscopy was used to examine the aqueous humor obtained via anterior chamber paracentesis and the anterior lens capsule obtained via intracapsular cataract extraction (ICCE), which revealed that the anterior lens capsule was intact. However, SEM revealed full-thickness disruptions in the anterior lens. CONCLUSION: This is the first reported case of phacolytic glaucoma with disruptions of the anterior lens capsule confirmed by SEM. BioMed Central 2014-11-19 /pmc/articles/PMC4251857/ /pubmed/25407294 http://dx.doi.org/10.1186/1471-2415-14-133 Text en © Yoo et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Yoo, Woong-Sun
Kim, Byeong-Jae
Chung, In-Young
Seo, Seong-Wook
Yoo, Ji-Myong
Kim, Seong-Jae
A case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy
title A case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy
title_full A case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy
title_fullStr A case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy
title_full_unstemmed A case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy
title_short A case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy
title_sort case of phacolytic glaucoma with anterior lens capsule disruption identified by scanning electron microscopy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251857/
https://www.ncbi.nlm.nih.gov/pubmed/25407294
http://dx.doi.org/10.1186/1471-2415-14-133
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