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Prosaposin Overexpression following Kainic Acid-Induced Neurotoxicity
Because excessive glutamate release is believed to play a pivotal role in numerous neuropathological disorders, such as ischemia or seizure, we aimed to investigate whether intrinsic prosaposin (PS), a neuroprotective factor when supplied exogenously in vivo or in vitro, is up-regulated after the ex...
Autores principales: | Nabeka, Hiroaki, Uematsu, Keigo, Takechi, Hiroko, Shimokawa, Tetsuya, Yamamiya, Kimiko, Li, Cheng, Doihara, Takuya, Saito, Shouichiro, Kobayashi, Naoto, Matsuda, Seiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251898/ https://www.ncbi.nlm.nih.gov/pubmed/25461957 http://dx.doi.org/10.1371/journal.pone.0110534 |
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