Profiling of Cxcl12 Receptors, Cxcr4 and Cxcr7 in Murine Testis Development and a Spermatogenic Depletion Model Indicates a Role for Cxcr7 in Controlling Cxcl12 Activity

In mice the chemokine Cxcl12 and its receptor Cxcr4 participate in maintenance of the spermatogonial population during postnatal development. More complexity arises since Cxcl12 also binds to the non-classical/atypical chemokine receptor Cxcr7. We explored the expression pattern of Cxcl12, Cxcr4 and...

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Detalles Bibliográficos
Autores principales: Westernströer, Birgit, Terwort, Nicole, Ehmcke, Jens, Wistuba, Joachim, Schlatt, Stefan, Neuhaus, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251904/
https://www.ncbi.nlm.nih.gov/pubmed/25460567
http://dx.doi.org/10.1371/journal.pone.0112598

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