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Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy
BACKGROUND: Epicardial injection of heart-derived cell products is safe and effective post-myocardial infarction (MI), but clinically-translatable transendocardial injection has never been evaluated. We sought to assess the feasibility, safety and efficacy of percutaneous transendocardial injection...
Autores principales: | Yee, Kristine, Malliaras, Konstantinos, Kanazawa, Hideaki, Tseliou, Eleni, Cheng, Ke, Luthringer, Daniel J., Ho, Chak-Sum, Takayama, Kentaro, Minamino, Naoto, Dawkins, James F., Chowdhury, Supurna, Duong, Doan Trang, Seinfeld, Jeffrey, Middleton, Ryan C., Dharmakumar, Rohan, Li, Debiao, Marbán, Linda, Makkar, Raj R., Marbán, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251970/ https://www.ncbi.nlm.nih.gov/pubmed/25460005 http://dx.doi.org/10.1371/journal.pone.0113805 |
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