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Contemporary Avian Influenza A Virus Subtype H1, H6, H7, H10, and H15 Hemagglutinin Genes Encode a Mammalian Virulence Factor Similar to the 1918 Pandemic Virus H1 Hemagglutinin
Zoonotic avian influenza virus infections may lead to epidemics or pandemics. The 1918 pandemic influenza virus has an avian influenza virus-like genome, and its H1 hemagglutinin was identified as a key mammalian virulence factor. A chimeric 1918 virus expressing a contemporary avian H1 hemagglutini...
Autores principales: | Qi, Li, Pujanauski, Lindsey M., Davis, A. Sally, Schwartzman, Louis M., Chertow, Daniel S., Baxter, David, Scherler, Kelsey, Hartshorn, Kevan L., Slemons, Richard D., Walters, Kathie-Anne, Kash, John C., Taubenberger, Jeffery K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251996/ https://www.ncbi.nlm.nih.gov/pubmed/25406382 http://dx.doi.org/10.1128/mBio.02116-14 |
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