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Sensitivity of leukemic T-cell lines to arsenic trioxide cytotoxicity is dependent on the induction of phosphatase B220/CD45R expression at the cell surface

BACKGROUND: Arsenic trioxide (As(2)O(3)) is highly effective in treating acute promyelocytic leukemia (APL), but shows more variable therapeutic efficacy for other types of hematological malignancies. Previously, we reported that As(2)O(3) selectively eliminates pathogenic B220-expressing T cells in...

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Detalles Bibliográficos
Autores principales:	Benbijja, Mohcine, Mellouk, Amine, Bobé, Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252024/ https://www.ncbi.nlm.nih.gov/pubmed/25410152 http://dx.doi.org/10.1186/1476-4598-13-251

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