Cargando…

A Novel In Vivo Model of Focal Light Emitting Diode-Induced Cone-Photoreceptor Phototoxicity: Neuroprotection Afforded by Brimonidine, BDNF, PEDF or bFGF

We have investigated the effects of light-emitting diode (LED)-induced phototoxicity (LIP) on cone-photoreceptors and their protection with brimonidine (BMD), brain-derived neurotrophic factor (BDNF), pigment epithelium-derived factor (PEDF), ciliary neurotrophic factor (CNTF) or basic fibroblast gr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ortín-Martínez, Arturo, Valiente-Soriano, Francisco Javier, García-Ayuso, Diego, Alarcón-Martínez, Luis, Jiménez-López, Manuel, Bernal-Garro, José Manuel, Nieto-López, Leticia, Nadal-Nicolás, Francisco Manuel, Villegas-Pérez, María Paz, Wheeler, Larry A., Vidal-Sanz, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252057/ https://www.ncbi.nlm.nih.gov/pubmed/25464513 http://dx.doi.org/10.1371/journal.pone.0113798

Ejemplares similares

Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2019)

Pigment Epithelium-Derived Factor (PEDF) Fragments Prevent Mouse Cone Photoreceptor Cell Loss Induced by Focal Phototoxicity In Vivo
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2020)

Sectorial loss of retinal ganglion cells in inherited photoreceptor degeneration is due to RGC death
por: García-Ayuso, Diego, et al.
Publicado: (2014)

Animal Models of LED-Induced Phototoxicity. Short- and Long-Term In Vivo and Ex Vivo Retinal Alterations
por: Miralles de Imperial-Ollero, Juan A., et al.
Publicado: (2021)

Systemic taurine treatment affords functional and morphological neuroprotection of photoreceptors and restores retinal pigment epithelium function in RCS rats()
por: Martínez-Vacas, Ana, et al.
Publicado: (2022)

Number and Distribution of Mouse Retinal Cone Photoreceptors: Differences between an Albino (Swiss) and a Pigmented (C57/BL6) Strain
por: Ortín-Martínez, Arturo, et al.
Publicado: (2014)

Short- and Long-Term Study of the Impact of Focal Blue Light-Emitting Diode-Induced Phototoxicity in Adult Albino Rats
por: Miralles de Imperial-Ollero, Juan A., et al.
Publicado: (2021)

Effects of Ocular Hypertension in the Visual System of Pigmented Mice
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2015)

Distribution of melanopsin positive neurons in pigmented and albino mice: evidence for melanopsin interneurons in the mouse retina
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2014)

Functional and morphological effects of laser-induced ocular hypertension in retinas of adult albino Swiss mice
por: Salinas-Navarro, Manuel, et al.
Publicado: (2009)

Role of microglial cells in photoreceptor degeneration
por: Di Pierdomenico, Johnny, et al.
Publicado: (2019)

Bone Marrow-Derived Mononuclear Cell Transplants Decrease Retinal Gliosis in Two Animal Models of Inherited Photoreceptor Degeneration
por: Di Pierdomenico, Johnny, et al.
Publicado: (2020)

Retinal Ganglion Cell Death as a Late Remodeling Effect of Photoreceptor Degeneration
por: García-Ayuso, Diego, et al.
Publicado: (2019)

Phototoxic damage to cone photoreceptors can be independent of the visual pigment: the porphyrin hypothesis
por: Marie, Mélanie, et al.
Publicado: (2020)

Melanopsin(+)RGCs Are fully Resistant to NMDA-Induced Excitotoxicity
por: Vidal-Villegas, Beatriz, et al.
Publicado: (2019)

Retinal remodeling following photoreceptor degeneration causes retinal ganglion cell death
por: García-Ayuso, Diego, et al.
Publicado: (2018)

Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells
Publicado: (1994)

Lipofuscins prepared by modification of photoreceptor cells via glycation or lipid peroxidation show the similar phototoxicity
por: Dontsov, Alexander, et al.
Publicado: (2016)

Glial Cell Activation and Oxidative Stress in Retinal Degeneration Induced by β-Alanine Caused Taurine Depletion and Light Exposure
por: Martínez-Vacas, Ana, et al.
Publicado: (2021)

PEDF and GDNF are key regulators of photoreceptor development and retinal neurogenesis in reaggregates from chick embryonic retina
por: Volpert, Katja N., et al.
Publicado: (2009)

Ablation of pigment epithelium-derived factor receptor (PEDF-R/Pnpla2) causes photoreceptor degeneration
por: Bernardo-Colón, Alexandra, et al.
Publicado: (2023)

Shared and Differential Retinal Responses against Optic Nerve Injury and Ocular Hypertension
por: Vidal-Sanz, Manuel, et al.
Publicado: (2017)

Identifying specific RGC types may shed light on their idiosyncratic responses to neuroprotection
por: Vidal-Sanz, Manuel, et al.
Publicado: (2015)

Expression of bFGF and VEGF in brain astrocytoma.
por: Shim, J. W., et al.
Publicado: (1996)

Oxidative Stress and Histological Changes in a Model of Retinal Phototoxicity in Rabbits
por: Saenz-de-Viteri, Manuel, et al.
Publicado: (2014)

Photoreceptor inputs to pupil control
por: Spitschan, Manuel
Publicado: (2019)

Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R)
por: Bullock, Jeanee, et al.
Publicado: (2021)

Pressure-Induced Alterations in PEDF and PEDF-R Expression: Implications for Neuroprotective Signaling in Glaucoma
por: Lee, Sean J, et al.
Publicado: (2015)

Displaced retinal ganglion cells in albino and pigmented rats
por: Nadal-Nicolás, Francisco M., et al.
Publicado: (2014)

Delivery of bFGF for Tissue Engineering by Tethering to the ECM
por: Suttinont, Chawapun, et al.
Publicado: (2015)

Biomaterial-Based bFGF Delivery for Nerve Repair
por: Huang, Qinying, et al.
Publicado: (2023)

Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo
por: Fontaine, Valérie, et al.
Publicado: (2016)

PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL
por: Zhang, Hao, et al.
Publicado: (2015)

Pigment Epithelium‐Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF‐R)
por: Lu, Peng, et al.
Publicado: (2016)

Active Pharmacovigilance in Peruvian Population: Surveillance of a Timolol/Brimonidine/Dorzolamide Ophthalmic Fixed Combination
por: Contreras-Salinas, Homero, et al.
Publicado: (2021)

Assessment of the Tissue Response to Modification of the Surface of Dental Implants with Carboxyethylphosphonic Acid and Basic Fibroblastic Growth Factor Immobilization (Fgf-2): An Experimental Study on Minipigs
por: Aragoneses, Javier, et al.
Publicado: (2021)

Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma
por: Madeira, Maria H., et al.
Publicado: (2016)

Randomized Trial of Brinzolamide/Brimonidine Versus Brinzolamide Plus Brimonidine for Open-Angle Glaucoma or Ocular Hypertension
por: Gandolfi, Stefano A., et al.
Publicado: (2014)

Crossover Randomized Study of Pharmacologic Effects of Ripasudil–Brimonidine Fixed-Dose Combination Versus Ripasudil or Brimonidine
por: Tanihara, Hidenobu, et al.
Publicado: (2023)

The Quantitative Analysis of bFGF and VEGF by ELISA in Human Meningiomas
por: Denizot, Yves, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_7sjjnb7lfhp5kdvr7pmlast2lt