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HIV-1 Infection Causes a Down-Regulation of Genes Involved in Ribosome Biogenesis
HIV-1 preferentially infects CD4(+) T cells, causing fundamental changes that eventually lead to the release of new viral particles and cell death. To investigate in detail alterations in the transcriptome of the CD4(+) T cells upon viral infection, we sequenced polyadenylated RNA isolated from Jurk...
Autores principales: | Kleinman, Claudia L., Doria, Margherita, Orecchini, Elisa, Giuliani, Erica, Galardi, Silvia, De Jay, Nicolas, Michienzi, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252078/ https://www.ncbi.nlm.nih.gov/pubmed/25462981 http://dx.doi.org/10.1371/journal.pone.0113908 |
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