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β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin
Ceruloplasmin is a ferroxidase that interacts with ferroportin to export cellular iron, but is not expressed in neurons. We recently reported that the amyloid precursor protein (APP) is the analogous iron-exporting chaperone for neurons and other cells. The ferroxidase activity of APP has since been...
Autores principales: | Wong, Bruce X., Tsatsanis, Andrew, Lim, Linh Q., Adlard, Paul A., Bush, Ashley I., Duce, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252103/ https://www.ncbi.nlm.nih.gov/pubmed/25464026 http://dx.doi.org/10.1371/journal.pone.0114174 |
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