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Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore
The aim of this study is to determine the efficacy of neoadjuvant chemotherapy (NAC) with gemcitabine (GEM) in combination with fluorescence-guided surgery (FGS) on a pancreatic cancer patient derived orthotopic xenograft (PDOX) model. A PDOX model was established from a CA19-9-positive, CEA-negativ...
Autores principales: | Hiroshima, Yukihiko, Maawy, Ali, Zhang, Yong, Murakami, Takashi, Momiyama, Masashi, Mori, Ryutaro, Matsuyama, Ryusei, Katz, Matthew H. G., Fleming, Jason B., Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Endo, Itaru, Hoffman, Robert M., Bouvet, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252107/ https://www.ncbi.nlm.nih.gov/pubmed/25463150 http://dx.doi.org/10.1371/journal.pone.0114310 |
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