Cargando…
Dishevelled Binds the Discs Large ‘Hook’ Domain to Activate GukHolder-Dependent Spindle Positioning in Drosophila
Communication between cortical cell polarity cues and the mitotic spindle ensures proper orientation of cell divisions within complex tissues. Defects in mitotic spindle positioning have been linked to various developmental disorders and have recently emerged as a potential contributor to tumorigene...
Autores principales: | Garcia, Joshua D., Dewey, Evan B., Johnston, Christopher A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252473/ https://www.ncbi.nlm.nih.gov/pubmed/25461409 http://dx.doi.org/10.1371/journal.pone.0114235 |
Ejemplares similares
-
The epithelial polarity genes frazzled and GUK-holder adjust morphogen gradients to coordinate changes in cell position with cell fate specification
por: Xue, Yongqiang, et al.
Publicado: (2023) -
Discs Large Links Spindle Orientation to Apical-Basal Polarity in Drosophila Epithelia
por: Bergstralh, Dan T., et al.
Publicado: (2013) -
Pins is not required for spindle orientation in the Drosophila wing disc
por: Bergstralh, Dan T., et al.
Publicado: (2016) -
The structural and functional determinants of the Axin and Dishevelled DIX domains
por: Ehebauer, Matthias T, et al.
Publicado: (2009) -
Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled
por: Gammons, Melissa V., et al.
Publicado: (2016)