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An autotransporter display platform for the development of multivalent recombinant bacterial vector vaccines
BACKGROUND: The Autotransporter pathway, ubiquitous in Gram-negative bacteria, allows the efficient secretion of large passenger proteins via a relatively simple mechanism. Capitalizing on its crystal structure, we have engineered the Escherichia coli autotransporter Hemoglobin protease (Hbp) into a...
Päätekijät: | , , , , , , , , , , , , |
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Aineistotyyppi: | Online Artikkeli Teksti |
Kieli: | English |
Julkaistu: |
BioMed Central
2014
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Aiheet: | |
Linkit: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252983/ https://www.ncbi.nlm.nih.gov/pubmed/25421093 http://dx.doi.org/10.1186/s12934-014-0162-8 |