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HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells
BACKGROUND: HIV-1, like all viruses, is entirely dependent on the host cell for providing the metabolic resources for completion of the viral replication cycle and the production of virions. It is well established that HIV-1 replicates efficiently in activated CD4+ T cells, whereas resting CD4+ T ce...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252996/ https://www.ncbi.nlm.nih.gov/pubmed/25421745 http://dx.doi.org/10.1186/s12977-014-0098-4 |