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HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells

BACKGROUND: HIV-1, like all viruses, is entirely dependent on the host cell for providing the metabolic resources for completion of the viral replication cycle and the production of virions. It is well established that HIV-1 replicates efficiently in activated CD4+ T cells, whereas resting CD4+ T ce...

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Detalles Bibliográficos
Autores principales: Hegedus, Andrea, Kavanagh Williamson, Maia, Huthoff, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252996/
https://www.ncbi.nlm.nih.gov/pubmed/25421745
http://dx.doi.org/10.1186/s12977-014-0098-4

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