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Ex vivo (1)H nuclear magnetic resonance spectroscopy reveals systematic alterations in cerebral metabolites as the key pathogenetic mechanism of bilirubin encephalopathy

BACKGROUND: Bilirubin encephalopathy (BE) is a severe neurologic sequelae induced by hyperbilirubinemia in newborns. However, the pathogenetic mechanisms underlying the clinical syndromes of BE remain ambiguous. Ex vivo(1)H nuclear magnetic resonance (NMR) spectroscopy was used to measure changes in...

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Detalles Bibliográficos
Autores principales: Hu, Wenyi, Cheng, Xiaojie, Ye, Xinjian, Zhao, Liangcai, Huang, Yanan, Zhu, Huanle, Yan, Zhihan, Wang, Xuebao, Wang, Xiaojie, Bai, Guanghui, Gao, Hongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252999/
https://www.ncbi.nlm.nih.gov/pubmed/25424547
http://dx.doi.org/10.1186/s13041-014-0087-5