In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential

The oncogenic bHLH-LZ transcription factor Myc forms binary complexes with its binding partner Max. These and other bHLH-LZ-based protein-protein interactions (PPI) in the Myc-Max network are essential for the physiological and oncogenic activities of Myc. We have generated a genetically determined...

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Detalles Bibliográficos
Autores principales: Raffeiner, Philipp, Röck, Ruth, Schraffl, Andrea, Hartl, Markus, Hart, Jonathan R., Janda, Kim D., Vogt, Peter K., Stefan, Eduard, Bister, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253403/
https://www.ncbi.nlm.nih.gov/pubmed/25326649

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