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Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials

BACKGROUND: KRAS mutation is common in human cancer. We assessed the clinical factors, including type of KRAS mutation and treatment, of patients with advanced cancer and tumor KRAS mutations and their association with treatment outcomes. METHODS: Patients referred to the Phase I Clinic for treatmen...

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Detalles Bibliográficos
Autores principales:	Said, Rabih, Ye, Yang, Falchook, Gerald Steven, Janku, Filip, Naing, Aung, Zinner, Ralph, Blumenschein, George R., Fu, Siqing, Hong, David S., Piha-Paul, Sarina Anne, Wheler, Jennifer J., Kurzrock, Razelle, Palmer, Gary A., Aldape, Kenneth, Hess, Kenneth R., Tsimberidou, Apostolia Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Clinical Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253408/ https://www.ncbi.nlm.nih.gov/pubmed/25313136

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