A novel tumor suppressor function of Kindlin-3 in solid cancer

Kindlin-3 (FERMT-3) is known to be central in hemostasis and thrombosis control and its deficiency disrupts platelet aggregation and causes Leukocyte Adhesion Deficiency disease. Here we report that Kindlin-3 has a tumor suppressive role in solid cancer. Our present genetic and functional data show...

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Detalles Bibliográficos
Autores principales: Djaafri, Ibtissem, Khayati, Farah, Menashi, Suzanne, Tost, Jorg, Podgorniak, Marie-Pierre, Sadoux, Aurelie, Daunay, Antoine, Teixeira, Luis, Soulier, Jean, Idbaih, Ahmed, Setterblad, Niclas, Fauvel, Françoise, Calvo, Fabien, Janin, Anne, Lebbé, Celeste, Mourah, Samia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253411/
https://www.ncbi.nlm.nih.gov/pubmed/25344860

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