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Dclk1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition
Doublecortin-like kinase 1 (Dclk1) is overexpressed in many cancers including colorectal cancer (CRC) and it specifically marks intestinal tumor stem cells. However, the role of Dclk1 in intestinal tumorigenesis in Apc mutant conditions is still poorly understood. We demonstrate that Dclk1 expressio...
Autores principales: | Chandrakesan, Parthasarathy, Weygant, Nathaniel, May, Randal, Qu, Dongfeng, Chinthalapally, Harisha R., Sureban, Sripathi M., Ali, Naushad, Lightfoot, Stan A., Umar, Shahid, Houchen, Courtney W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253433/ https://www.ncbi.nlm.nih.gov/pubmed/25211188 |
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