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Transcriptional coactivator CBP upregulates hTERT expression and tumor growth and predicts poor prognosis in human lung cancers
Upregulated expression and activation of human telomerase reverse transcriptase (hTERT) is a hallmarker of lung tumorigenesis. However, the mechanism underlying the aberrant hTERT activity in lung cancer cells remains poorly understood. In this study, we found the transcriptional co-activator CBP as...
Autores principales: | Guo, Wei, Lu, Jianjun, Dai, Meng, Wu, Taihua, Yu, Zhenlong, Wang, Jingshu, Chen, Wangbing, Shi, Dingbo, Yu, Wendan, Xiao, Yao, Yi, Canhui, Tang, Zhipeng, Xu, Tingting, Xiao, Xiangsheng, Yuan, Yuhui, Liu, Quentin, Du, Guangwei, Deng, Wuguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253439/ https://www.ncbi.nlm.nih.gov/pubmed/25294805 |
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