The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer

Inhibition of FASN has emerged as a promising therapeutic target in cancer, and numerous inhibitors have been investigated. However, severe pharmacological limitations have challenged their clinical testing. The synthetic FASN inhibitor triclosan, which was initially developed as a topical antibacte...

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Detalles Bibliográficos
Autores principales: Sadowski, Martin C., Pouwer, Rebecca H., Gunter, Jennifer H., Lubik, Amy A., Quinn, Ronald J., Nelson, Colleen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253440/
https://www.ncbi.nlm.nih.gov/pubmed/25313139

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