The DNA2 nuclease/helicase is an estrogen-dependent gene mutated in breast and ovarian cancers

Genomic instability, a hallmark of cancer, is commonly caused by failures in the DNA damage response. Here we conducted a bioinformatical screen to reveal DNA damage response genes that are upregulated by estrogen and highly mutated in breast and ovarian cancers. This screen identified 53 estrogen-d...

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Detalles Bibliográficos
Autores principales: Strauss, Carmit, Kornowski, Maya, Benvenisty, Avraham, Shahar, Amit, Masury, Hadas, Ben-Porath, Ittai, Ravid, Tommer, Arbel-Eden, Ayelet, Goldberg, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253442/
https://www.ncbi.nlm.nih.gov/pubmed/25238049

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