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Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart
Hypoxic exposure is associated with impaired cardiac energetics in humans and altered mitochondrial function, with suppressed complex I-supported respiration, in rat heart. This response might limit reactive oxygen species generation, but at the cost of impaired electron transport chain (ETC) activi...
Autores principales: | Ashmore, Tom, Fernandez, Bernadette O, Branco-Price, Cristina, West, James A, Cowburn, Andrew S, Heather, Lisa C, Griffin, Julian L, Johnson, Randall S, Feelisch, Martin, Murray, Andrew J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253472/ https://www.ncbi.nlm.nih.gov/pubmed/25172947 http://dx.doi.org/10.1113/jphysiol.2014.275263 |
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