Cargando…

Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart

Hypoxic exposure is associated with impaired cardiac energetics in humans and altered mitochondrial function, with suppressed complex I-supported respiration, in rat heart. This response might limit reactive oxygen species generation, but at the cost of impaired electron transport chain (ETC) activi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ashmore, Tom, Fernandez, Bernadette O, Branco-Price, Cristina, West, James A, Cowburn, Andrew S, Heather, Lisa C, Griffin, Julian L, Johnson, Randall S, Feelisch, Martin, Murray, Andrew J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Cardiovascular
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253472/ https://www.ncbi.nlm.nih.gov/pubmed/25172947 http://dx.doi.org/10.1113/jphysiol.2014.275263

Ejemplares similares

Suppression of erythropoiesis by dietary nitrate
por: Ashmore, Tom, et al.
Publicado: (2015)

Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism
por: Ashmore, Tom, et al.
Publicado: (2015)

Synthesis, Characterization, and Energetic Properties of Nitrate Ester Acrylate Polymer
por: Kuehl, Valerie A., et al.
Publicado: (2023)

Acute hemodynamic effects of L-arginine, arginine nitrate, and arginine peptide on exercise-induced vasodilation and blood flow in healthy men
por: Falcone, Paul H, et al.
Publicado: (2015)

Nitration of Chitin Monomer: From Glucosamine to Energetic Compound
por: Dou, Hui, et al.
Publicado: (2021)

Endothelial hypoxic metabolism in carcinogenesis and dissemination : HIF-A isoforms are a NO metastatic phenomenon
por: Branco-Price, Cristina, et al.
Publicado: (2013)

Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study
por: Rathod, Krishnaraj S, et al.
Publicado: (2016)

Effects of dietary nitrate on respiratory physiology at high altitude - Results from the Xtreme Alps study
por: Cumpstey, Andrew F., et al.
Publicado: (2017)

Leucine and Arginine Availability Modulate Mouse Embryonic Stem Cell Proliferation and Metabolism
por: Correia, Bibiana, et al.
Publicado: (2022)

Examining the chemical and structural properties that influence the sensitivity of energetic nitrate esters
por: Manner, Virginia W., et al.
Publicado: (2018)

Recent Advances in Synthesis and Properties of Nitrated-Pyrazoles Based Energetic Compounds
por: Zhang, Shijie, et al.
Publicado: (2020)

Determinants of improvement of left ventricular mechano-energetic efficiency in hypertensive patients
por: Lembo, Maria, et al.
Publicado: (2022)

Dietary inorganic nitrate: From villain to hero in metabolic disease?
por: McNally, Ben, et al.
Publicado: (2015)

The effect of cardioplegic supplementation with sildenafil on cardiac energetics in a piglet model of cardiopulmonary bypass and cardioplegic arrest with warm or cold cardioplegia
por: Skeffington, Katie L., et al.
Publicado: (2023)

Dual role of the L-arginine–ADMA–NO pathway in systemic hypoxic vasodilation and pulmonary hypoxic vasoconstriction
por: Böger, Rainer, et al.
Publicado: (2020)

Hypoxic pulmonary vasoconstriction in isolated rat pulmonary arteries is not inhibited by antagonists of H(2)S-synthesizing pathways
por: Prieto-Lloret, Jesus, et al.
Publicado: (2015)

Effects of inorganic nitrate on ischaemia-reperfusion injury after coronary artery bypass surgery: a randomised controlled trial
por: Eriksson, Karin E., et al.
Publicado: (2021)

Vegetable nitrate intake, blood pressure and incident cardiovascular disease: Danish Diet, Cancer, and Health Study
por: Bondonno, Catherine P., et al.
Publicado: (2021)

Randomised, double-blind, placebo-controlled clinical trial investigating the effects of inorganic nitrate in hypertension-induced target organ damage: protocol of the NITRATE-TOD study in the UK
por: Lau, Clement Wai Zhen, et al.
Publicado: (2020)

Household availability of dietary fats and cardiovascular disease and mortality: prospective evidence from Russia
por: Stefler, Denes, et al.
Publicado: (2021)

L-Arginine Improves Cognitive Impairment in Hypertensive Frail Older Adults
por: Mone, Pasquale, et al.
Publicado: (2022)

THIRSTY FOR FRUCTOSE: Arginine Vasopressin, Fructose, and the Pathogenesis of Metabolic and Renal Disease
por: Student, Jeffrey, et al.
Publicado: (2022)

Effects of dietary nitrate supplementation on microvascular physiology at 4559 m altitude – A randomised controlled trial (Xtreme Alps)
por: Cumpstey, Andrew F., et al.
Publicado: (2020)

Dietary Nitrate Supplementation Does Not Alter Exercise Efficiency at High Altitude – Further Results From the Xtreme Alps Study
por: Hennis, Philip J., et al.
Publicado: (2022)

Cardiac Energetics Before, During, and After Anthracycline-Based Chemotherapy in Breast Cancer Patients Using (31)P Magnetic Resonance Spectroscopy: A Pilot Study
por: Macnaught, Gillian, et al.
Publicado: (2021)

Sulfate, nitrate and blood pressure – An EPIC interaction between sulfur and nitrogen
por: Kuhnle, Gunter G., et al.
Publicado: (2017)

ReaxFF Molecular Dynamics Simulation of Hydrostatic and Uniaxial Compression of Nitrate Energetic Materials
por: Zhang, Yaping, et al.
Publicado: (2020)

Solid‐State and Gas‐Phase Structures and Energetic Properties of the Dangerous Methyl and Fluoromethyl Nitrates
por: Reichel, Marco, et al.
Publicado: (2019)

Impact of dobutamine stress on diastolic energetic efficiency of healthy left ventricle: an in vivo kinetic energy analysis
por: Riva, Alessandra, et al.
Publicado: (2023)

Dietary Nitrate Supplementation and Exercise Performance
por: Jones, Andrew M.
Publicado: (2014)

Multiple abiotic stress, nitrate availability and the growth of wheat
por: Ge, Y., et al.
Publicado: (2019)

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue
por: Roberts, Lee D, et al.
Publicado: (2011)

Efficacy and safety of inorganic nitrate/nitrite supplementary therapy in heart failure with preserved ejection fraction
por: Lv, Feng, et al.
Publicado: (2023)

Arginine-vasopressin marker copeptin is a sensitive plasma surrogate of hypoxic exposure
por: Ostergaard, Louise, et al.
Publicado: (2014)

Extracellular Vesicles Secreted by Hypoxic AC10 Cardiomyocytes Modulate Fibroblast Cell Motility
por: Ontoria-Oviedo, Imelda, et al.
Publicado: (2018)

The Effects of Intermittent Hypoxic–Hyperoxic Exposures on Lipid Profile and Inflammation in Patients With Metabolic Syndrome
por: Afina, A. Bestavashvili, et al.
Publicado: (2021)

Energetic substrate availability regulates synchronous activity in an excitatory neural network
por: Tourigny, David S., et al.
Publicado: (2019)

Melatonin Attenuates Dasatinib-Aggravated Hypoxic Pulmonary Hypertension via Inhibiting Pulmonary Vascular Remodeling
por: Wang, Rui, et al.
Publicado: (2022)

Dietary Nitrate Supplementation Is Not Helpful for Endurance Performance at Simulated Altitude Even When Combined With Intermittent Normobaric Hypoxic Training
por: Sousa, Ana, et al.
Publicado: (2022)

Human skeletal muscle nitrate store: influence of dietary nitrate supplementation and exercise
por: Wylie, Lee J., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vm312jmh082jjdjb81jhef64sh