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TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator

BACKGROUND: Hypoxia induces the epithelial-mesenchymal transition, EMT, to promote cancer metastasis. In addition to transcriptional regulation mediated by hypoxia-inducible factors, HIFs, other epigenetic mechanisms of gene regulation, such as histone modifications and DNA methylation, are utilized...

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Detalles Bibliográficos
Autores principales:	Tsai, Ya-Ping, Chen, Hsiao-Fan, Chen, Sung-Yuan, Cheng, Wei-Chung, Wang, Hsei-Wei, Shen, Zih-Jie, Song, Chunxiao, Teng, Shu-Chun, He, Chuan, Wu, Kou-Juey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253621/ https://www.ncbi.nlm.nih.gov/pubmed/25517638 http://dx.doi.org/10.1186/s13059-014-0513-0

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