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OX40L blockade and allergen-induced airway responses in subjects with mild asthma

BACKGROUND: The OX40/OX40L interaction contributes to an optimal T cell response following allergic stimuli and plays an important role in the maintenance and reactivation of memory T effector cells. OBJECTIVE: We tested whether treatment with an anti-OX40L monoclonal antibody (MAb) would inhibit al...

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Detalles Bibliográficos
Autores principales: Gauvreau, G M, Boulet, L-P, Cockcroft, D W, FitzGerald, J M, Mayers, I, Carlsten, C, Laviolette, M, Killian, K J, Davis, B E, Larché, M, Kipling, C, Dua, B, Mosesova, S, Putnam, W, Zheng, Y, Scheerens, H, McClintock, D, Matthews, J G, O'Byrne, P M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253735/
https://www.ncbi.nlm.nih.gov/pubmed/24224471
http://dx.doi.org/10.1111/cea.12235

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