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The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement

BACKGROUND: Sub-valvular apparatus preservation (SAP) during mitral valve replacement (MVR) is not a new concept. Some surgeons prefer to excise the apparatus. OBJECTIVES: The aim of this study was to reduce the risk of prosthetic valve dysfunction. MATERIALS AND METHODS: This retrospective study in...

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Autores principales: Alizadeh-Ghavidel, Alireza, Mirmesdagh, Yalda, Sharifi, Mehrzad, Sadeghpour, Anita, Nakhaeizadeh, Reza, Omrani, Gholamreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253750/
https://www.ncbi.nlm.nih.gov/pubmed/25478491
http://dx.doi.org/10.5812/cardiovascmed.8054
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author Alizadeh-Ghavidel, Alireza
Mirmesdagh, Yalda
Sharifi, Mehrzad
Sadeghpour, Anita
Nakhaeizadeh, Reza
Omrani, Gholamreza
author_facet Alizadeh-Ghavidel, Alireza
Mirmesdagh, Yalda
Sharifi, Mehrzad
Sadeghpour, Anita
Nakhaeizadeh, Reza
Omrani, Gholamreza
author_sort Alizadeh-Ghavidel, Alireza
collection PubMed
description BACKGROUND: Sub-valvular apparatus preservation (SAP) during mitral valve replacement (MVR) is not a new concept. Some surgeons prefer to excise the apparatus. OBJECTIVES: The aim of this study was to reduce the risk of prosthetic valve dysfunction. MATERIALS AND METHODS: This retrospective study included 151 patients with the mean age of 46 years who underwent MVR (Female/male = 93/58). In the group I consisting of 39 patients, MVR with chordae preservation was performed (Bi-leaflet preservation = 20; posterior leaflet preservation = 19). In the group II consisting of 112 patients, sub-valvular apparatus was resected completely during MVR. Preoperative patients’ characteristics, including age, sex, functional status, left ventricular ejection fraction, and end-diastolic or end-systolic dimensions were statistically similar in both groups. Mean follow-up period was 60.3 ± 26 months. RESULTS: The improvement of functional status was seen in almost all survivors but was more obvious in the group I. In early follow-up, 56.4% of group I cases and 44.1% of group II patients were classified as New York Heart Association class I. These rates were 84.2% and 71.2% in mid-term follow-up, respectively (P < 0.001). Mortality rate was significantly lower in the group I (2.6%) compared to the group II (8.9%) (P = 0.03). There was a trend for higher frequency of postoperative atrial fibrillation in the group II compared to that in the group I (52.7% vs. 38.5%, P = 0.12).The incidence of prosthetic valve dysfunction (PVD) was 5.1% in the group I and 4.5% in the group II, but this difference was not statistically significant (P = 0.56). CONCLUSIONS: Preservation of mitral annulus and papillary muscle continuity may enhance post- MVR cardiac performance with low mortality and morbidity rates. The risk of PVD was not significantly higher than conventional MVR in our series.
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spelling pubmed-42537502014-12-04 The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement Alizadeh-Ghavidel, Alireza Mirmesdagh, Yalda Sharifi, Mehrzad Sadeghpour, Anita Nakhaeizadeh, Reza Omrani, Gholamreza Res Cardiovasc Med Original Article BACKGROUND: Sub-valvular apparatus preservation (SAP) during mitral valve replacement (MVR) is not a new concept. Some surgeons prefer to excise the apparatus. OBJECTIVES: The aim of this study was to reduce the risk of prosthetic valve dysfunction. MATERIALS AND METHODS: This retrospective study included 151 patients with the mean age of 46 years who underwent MVR (Female/male = 93/58). In the group I consisting of 39 patients, MVR with chordae preservation was performed (Bi-leaflet preservation = 20; posterior leaflet preservation = 19). In the group II consisting of 112 patients, sub-valvular apparatus was resected completely during MVR. Preoperative patients’ characteristics, including age, sex, functional status, left ventricular ejection fraction, and end-diastolic or end-systolic dimensions were statistically similar in both groups. Mean follow-up period was 60.3 ± 26 months. RESULTS: The improvement of functional status was seen in almost all survivors but was more obvious in the group I. In early follow-up, 56.4% of group I cases and 44.1% of group II patients were classified as New York Heart Association class I. These rates were 84.2% and 71.2% in mid-term follow-up, respectively (P < 0.001). Mortality rate was significantly lower in the group I (2.6%) compared to the group II (8.9%) (P = 0.03). There was a trend for higher frequency of postoperative atrial fibrillation in the group II compared to that in the group I (52.7% vs. 38.5%, P = 0.12).The incidence of prosthetic valve dysfunction (PVD) was 5.1% in the group I and 4.5% in the group II, but this difference was not statistically significant (P = 0.56). CONCLUSIONS: Preservation of mitral annulus and papillary muscle continuity may enhance post- MVR cardiac performance with low mortality and morbidity rates. The risk of PVD was not significantly higher than conventional MVR in our series. Kowsar 2013-02-24 2013-02 /pmc/articles/PMC4253750/ /pubmed/25478491 http://dx.doi.org/10.5812/cardiovascmed.8054 Text en Copyright © 2013, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran; Published by Kowsar Corp. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Alizadeh-Ghavidel, Alireza
Mirmesdagh, Yalda
Sharifi, Mehrzad
Sadeghpour, Anita
Nakhaeizadeh, Reza
Omrani, Gholamreza
The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement
title The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement
title_full The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement
title_fullStr The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement
title_full_unstemmed The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement
title_short The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement
title_sort impact of sub-valvular apparatus preservation on prosthetic valve dysfunction during mitral valve replacement
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253750/
https://www.ncbi.nlm.nih.gov/pubmed/25478491
http://dx.doi.org/10.5812/cardiovascmed.8054
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