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The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement
BACKGROUND: Sub-valvular apparatus preservation (SAP) during mitral valve replacement (MVR) is not a new concept. Some surgeons prefer to excise the apparatus. OBJECTIVES: The aim of this study was to reduce the risk of prosthetic valve dysfunction. MATERIALS AND METHODS: This retrospective study in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253750/ https://www.ncbi.nlm.nih.gov/pubmed/25478491 http://dx.doi.org/10.5812/cardiovascmed.8054 |
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author | Alizadeh-Ghavidel, Alireza Mirmesdagh, Yalda Sharifi, Mehrzad Sadeghpour, Anita Nakhaeizadeh, Reza Omrani, Gholamreza |
author_facet | Alizadeh-Ghavidel, Alireza Mirmesdagh, Yalda Sharifi, Mehrzad Sadeghpour, Anita Nakhaeizadeh, Reza Omrani, Gholamreza |
author_sort | Alizadeh-Ghavidel, Alireza |
collection | PubMed |
description | BACKGROUND: Sub-valvular apparatus preservation (SAP) during mitral valve replacement (MVR) is not a new concept. Some surgeons prefer to excise the apparatus. OBJECTIVES: The aim of this study was to reduce the risk of prosthetic valve dysfunction. MATERIALS AND METHODS: This retrospective study included 151 patients with the mean age of 46 years who underwent MVR (Female/male = 93/58). In the group I consisting of 39 patients, MVR with chordae preservation was performed (Bi-leaflet preservation = 20; posterior leaflet preservation = 19). In the group II consisting of 112 patients, sub-valvular apparatus was resected completely during MVR. Preoperative patients’ characteristics, including age, sex, functional status, left ventricular ejection fraction, and end-diastolic or end-systolic dimensions were statistically similar in both groups. Mean follow-up period was 60.3 ± 26 months. RESULTS: The improvement of functional status was seen in almost all survivors but was more obvious in the group I. In early follow-up, 56.4% of group I cases and 44.1% of group II patients were classified as New York Heart Association class I. These rates were 84.2% and 71.2% in mid-term follow-up, respectively (P < 0.001). Mortality rate was significantly lower in the group I (2.6%) compared to the group II (8.9%) (P = 0.03). There was a trend for higher frequency of postoperative atrial fibrillation in the group II compared to that in the group I (52.7% vs. 38.5%, P = 0.12).The incidence of prosthetic valve dysfunction (PVD) was 5.1% in the group I and 4.5% in the group II, but this difference was not statistically significant (P = 0.56). CONCLUSIONS: Preservation of mitral annulus and papillary muscle continuity may enhance post- MVR cardiac performance with low mortality and morbidity rates. The risk of PVD was not significantly higher than conventional MVR in our series. |
format | Online Article Text |
id | pubmed-4253750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Kowsar |
record_format | MEDLINE/PubMed |
spelling | pubmed-42537502014-12-04 The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement Alizadeh-Ghavidel, Alireza Mirmesdagh, Yalda Sharifi, Mehrzad Sadeghpour, Anita Nakhaeizadeh, Reza Omrani, Gholamreza Res Cardiovasc Med Original Article BACKGROUND: Sub-valvular apparatus preservation (SAP) during mitral valve replacement (MVR) is not a new concept. Some surgeons prefer to excise the apparatus. OBJECTIVES: The aim of this study was to reduce the risk of prosthetic valve dysfunction. MATERIALS AND METHODS: This retrospective study included 151 patients with the mean age of 46 years who underwent MVR (Female/male = 93/58). In the group I consisting of 39 patients, MVR with chordae preservation was performed (Bi-leaflet preservation = 20; posterior leaflet preservation = 19). In the group II consisting of 112 patients, sub-valvular apparatus was resected completely during MVR. Preoperative patients’ characteristics, including age, sex, functional status, left ventricular ejection fraction, and end-diastolic or end-systolic dimensions were statistically similar in both groups. Mean follow-up period was 60.3 ± 26 months. RESULTS: The improvement of functional status was seen in almost all survivors but was more obvious in the group I. In early follow-up, 56.4% of group I cases and 44.1% of group II patients were classified as New York Heart Association class I. These rates were 84.2% and 71.2% in mid-term follow-up, respectively (P < 0.001). Mortality rate was significantly lower in the group I (2.6%) compared to the group II (8.9%) (P = 0.03). There was a trend for higher frequency of postoperative atrial fibrillation in the group II compared to that in the group I (52.7% vs. 38.5%, P = 0.12).The incidence of prosthetic valve dysfunction (PVD) was 5.1% in the group I and 4.5% in the group II, but this difference was not statistically significant (P = 0.56). CONCLUSIONS: Preservation of mitral annulus and papillary muscle continuity may enhance post- MVR cardiac performance with low mortality and morbidity rates. The risk of PVD was not significantly higher than conventional MVR in our series. Kowsar 2013-02-24 2013-02 /pmc/articles/PMC4253750/ /pubmed/25478491 http://dx.doi.org/10.5812/cardiovascmed.8054 Text en Copyright © 2013, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran; Published by Kowsar Corp. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Alizadeh-Ghavidel, Alireza Mirmesdagh, Yalda Sharifi, Mehrzad Sadeghpour, Anita Nakhaeizadeh, Reza Omrani, Gholamreza The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement |
title | The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement |
title_full | The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement |
title_fullStr | The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement |
title_full_unstemmed | The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement |
title_short | The Impact of Sub-valvular Apparatus Preservation on Prosthetic Valve Dysfunction During Mitral Valve Replacement |
title_sort | impact of sub-valvular apparatus preservation on prosthetic valve dysfunction during mitral valve replacement |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253750/ https://www.ncbi.nlm.nih.gov/pubmed/25478491 http://dx.doi.org/10.5812/cardiovascmed.8054 |
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