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Tel1(ATM) dictates the replication timing of short yeast telomeres

Telomerase action is temporally linked to DNA replication. Although yeast telomeres are normally late replicating, telomere shortening leads to early firing of subtelomeric DNA replication origins. We show that double-strand breaks flanked by short telomeric arrays cause origin firing early in S pha...

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Detalles Bibliográficos
Autores principales: Cooley, Carol, Davé, Anoushka, Garg, Mansi, Bianchi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253850/
https://www.ncbi.nlm.nih.gov/pubmed/25122631
http://dx.doi.org/10.15252/embr.201439242