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cAMP controls the restoration of endothelial barrier function after thrombin‐induced hyperpermeability via Rac1 activation

Inflammatory mediators like thrombin disrupt endothelial adherens junctions (AJs) and barrier integrity leading to oedema formation followed by resealing of AJs and a slow recovery of the barrier function. The molecular mechanisms of this process have not yet been fully delineated. The aim of the pr...

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Detalles Bibliográficos
Autores principales: Aslam, Muhammad, Tanislav, Christian, Troidl, Christian, Schulz, Rainer, Hamm, Christian, Gündüz, Dursun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254100/
https://www.ncbi.nlm.nih.gov/pubmed/25344477
http://dx.doi.org/10.14814/phy2.12175