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cAMP controls the restoration of endothelial barrier function after thrombin‐induced hyperpermeability via Rac1 activation
Inflammatory mediators like thrombin disrupt endothelial adherens junctions (AJs) and barrier integrity leading to oedema formation followed by resealing of AJs and a slow recovery of the barrier function. The molecular mechanisms of this process have not yet been fully delineated. The aim of the pr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wiley Periodicals, Inc.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254100/ https://www.ncbi.nlm.nih.gov/pubmed/25344477 http://dx.doi.org/10.14814/phy2.12175 |