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Western blot analysis of BK channel β1‐subunit expression should be interpreted cautiously when using commercially available antibodies

Large conductance Ca(2+)‐activated K(+) (BK) channels consist of pore‐forming α‐ and accessory β‐subunits. There are four β‐subunit subtypes (β1–β4), BK β1‐subunit is specific for smooth muscle cells (SMC). Reduced BK β1‐subunit expression is associated with SMC dysfunction in animal models of human...

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Detalles Bibliográficos
Autores principales: Bhattarai, Yogesh, Fernandes, Roxanne, Kadrofske, Mark M., Lockwood, Lizbeth R., Galligan, James J., Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254108/
https://www.ncbi.nlm.nih.gov/pubmed/25355855
http://dx.doi.org/10.14814/phy2.12189