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Akt Activation is Required for TGF-β1-Induced Osteoblast Differentiation of MC3T3-E1 Pre-Osteoblasts

BACKGROUND: We have previously reported that repeated treatment of human periodontal ligament cells and murine pre-osteoblast MC3T3-E1 cells with transforming growth factor-beta 1 (TGF-β1) inhibited their osteoblastic differentiation because of decreased insulin-like growth factor-1 (IGF-1) secretio...

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Detalles Bibliográficos
Autores principales:	Suzuki, Eiichi, Ochiai-Shino, Hiromi, Aoki, Hideto, Onodera, Shoko, Saito, Akiko, Saito, Atsushi, Azuma, Toshifumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254279/ https://www.ncbi.nlm.nih.gov/pubmed/25470129 http://dx.doi.org/10.1371/journal.pone.0112566

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