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CRISPR-mediated genome editing of Plasmodium falciparum malaria parasites
The development of the CRISPR-Cas system is revolutionizing genome editing in a variety of organisms. The system has now been used to manipulate the genome of Plasmodium falciparum, the most lethal malaria-causing species. The ability to generate gene deletions or nucleotide substitutions rapidly an...
Autores principales: | Lee, Marcus CS, Fidock, David A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254425/ https://www.ncbi.nlm.nih.gov/pubmed/25473431 http://dx.doi.org/10.1186/s13073-014-0063-9 |
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