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A Chemical Proteomics Approach for the Search of Pharmacological Targets of the Antimalarial Clinical Candidate Albitiazolium in Plasmodium falciparum Using Photocrosslinking and Click Chemistry

Plasmodium falciparum is responsible for severe malaria which is one of the most prevalent and deadly infectious diseases in the world. The antimalarial therapeutic arsenal is hampered by the onset of resistance to all known pharmacological classes of compounds, so new drugs with novel mechanisms of...

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Detalles Bibliográficos
Autores principales: Penarete-Vargas, Diana Marcela, Boisson, Anaïs, Urbach, Serge, Chantelauze, Hervé, Peyrottes, Suzanne, Fraisse, Laurent, Vial, Henri J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254740/
https://www.ncbi.nlm.nih.gov/pubmed/25470252
http://dx.doi.org/10.1371/journal.pone.0113918