Computational and synthetic studies towards improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment

We, and others, have previously shown that mismatch repair proteins, in addition to their repair function, contribute to cell death initiation. In response to some drugs, this cell death activity is independent of the repair function of the proteins. Rescinnamine, a derivative of the indole alkaloid...

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Detalles Bibliográficos
Autores principales: AbdelHafez, ElShimaa M. N., Diamanduros, Andrew, Negureanu, Lacramioara, Luy, Yan, Bean, J. Hayley, Zielke, Katherine, Crowe, Brittany, Vasilyeva, Aksana, Clodfelter, Jill E., Aly, Omar M., Abuo-Rahma, Gamal El-Din A. A., Scarpinato, Karin D., Salsbury, Freddie R., King, S. Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254817/
https://www.ncbi.nlm.nih.gov/pubmed/25485184

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