Cargando…
Lenalidomide Induces Lipid Raft Assembly to Enhance Erythropoietin Receptor Signaling in Myelodysplastic Syndrome Progenitors
Anemia remains the principal management challenge for patients with lower risk Myelodysplastic Syndromes (MDS). Despite appropriate cytokine production and cellular receptor display, erythropoietin receptor (EpoR) signaling is impaired. We reported that EpoR signaling is dependent upon receptor loca...
Autores principales: | McGraw, Kathy L., Basiorka, Ashley A., Johnson, Joseph O., Clark, Justine, Caceres, Gisela, Padron, Eric, Heaton, Ruth, Ozawa, Yukiyasu, Wei, Sheng, Sokol, Lubomir, List, Alan F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254997/ https://www.ncbi.nlm.nih.gov/pubmed/25469886 http://dx.doi.org/10.1371/journal.pone.0114249 |
Ejemplares similares
-
Erythropoietin Receptor Signaling Is Membrane Raft Dependent
por: McGraw, Kathy L., et al.
Publicado: (2012) -
Dual pyroptotic biomarkers predict erythroid response in lower-risk non-del(5q) myelodysplastic syndromes treated with lenalidomide and recombinant erythropoietin
por: Wang, Chen, et al.
Publicado: (2021) -
Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes
por: Cluzeau, Thomas, et al.
Publicado: (2017) -
TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes
por: McGraw, Kathy L., et al.
Publicado: (2015) -
Reversal of T-cell Tolerance in Myelodysplastic Syndrome through Lenalidomide Immune Modulation
por: McDaniel, Jessica M., et al.
Publicado: (2011)