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Optimization of the Ethanol Recycling Reflux Extraction Process for Saponins Using a Design Space Approach

A solvent recycling reflux extraction process for Panax notoginseng was optimized using a design space approach to improve the batch-to-batch consistency of the extract. Saponin yields, total saponin purity, and pigment yield were defined as the process critical quality attributes (CQAs). Ethanol co...

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Detalles Bibliográficos
Autores principales: Gong, Xingchu, Zhang, Ying, Pan, Jianyang, Qu, Haibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255001/
https://www.ncbi.nlm.nih.gov/pubmed/25470598
http://dx.doi.org/10.1371/journal.pone.0114300

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