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Optimization of the Ethanol Recycling Reflux Extraction Process for Saponins Using a Design Space Approach
A solvent recycling reflux extraction process for Panax notoginseng was optimized using a design space approach to improve the batch-to-batch consistency of the extract. Saponin yields, total saponin purity, and pigment yield were defined as the process critical quality attributes (CQAs). Ethanol co...
Autores principales: | Gong, Xingchu, Zhang, Ying, Pan, Jianyang, Qu, Haibin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255001/ https://www.ncbi.nlm.nih.gov/pubmed/25470598 http://dx.doi.org/10.1371/journal.pone.0114300 |
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