Different Resting-State Functional Connectivity Alterations in Smokers and Nonsmokers with Internet Gaming Addiction

This study investigated changes in resting-state functional connectivity (rsFC) of posterior cingulate cortex (PCC) in smokers and nonsmokers with Internet gaming addiction (IGA). Twenty-nine smokers with IGA, 22 nonsmokers with IGA, and 30 healthy controls (HC group) underwent a resting-state fMRI...

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Autores principales: Chen, Xue, Wang, Yao, Zhou, Yan, Sun, Yawen, Ding, Weina, Zhuang, Zhiguo, Xu, Jianrong, Du, Yasong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255056/
https://www.ncbi.nlm.nih.gov/pubmed/25506057
http://dx.doi.org/10.1155/2014/825787
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author Chen, Xue
Wang, Yao
Zhou, Yan
Sun, Yawen
Ding, Weina
Zhuang, Zhiguo
Xu, Jianrong
Du, Yasong
author_facet Chen, Xue
Wang, Yao
Zhou, Yan
Sun, Yawen
Ding, Weina
Zhuang, Zhiguo
Xu, Jianrong
Du, Yasong
author_sort Chen, Xue
collection PubMed
description This study investigated changes in resting-state functional connectivity (rsFC) of posterior cingulate cortex (PCC) in smokers and nonsmokers with Internet gaming addiction (IGA). Twenty-nine smokers with IGA, 22 nonsmokers with IGA, and 30 healthy controls (HC group) underwent a resting-state fMRI scan. PCC connectivity was determined in all subjects by investigating synchronized low-frequency fMRI signal fluctuations using a temporal correlation method. Compared with the nonsmokers with IGA, the smokers with IGA exhibited decreased rsFC with PCC in the right rectus gyrus. Left middle frontal gyrus exhibited increased rsFC. The PCC connectivity with the right rectus gyrus was found to be negatively correlated with the CIAS scores in the smokers with IGA before correction. Our results suggested that smokers with IGA had functional changes in brain areas related to motivation and executive function compared with the nonsmokers with IGA.
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spelling pubmed-42550562014-12-11 Different Resting-State Functional Connectivity Alterations in Smokers and Nonsmokers with Internet Gaming Addiction Chen, Xue Wang, Yao Zhou, Yan Sun, Yawen Ding, Weina Zhuang, Zhiguo Xu, Jianrong Du, Yasong Biomed Res Int Research Article This study investigated changes in resting-state functional connectivity (rsFC) of posterior cingulate cortex (PCC) in smokers and nonsmokers with Internet gaming addiction (IGA). Twenty-nine smokers with IGA, 22 nonsmokers with IGA, and 30 healthy controls (HC group) underwent a resting-state fMRI scan. PCC connectivity was determined in all subjects by investigating synchronized low-frequency fMRI signal fluctuations using a temporal correlation method. Compared with the nonsmokers with IGA, the smokers with IGA exhibited decreased rsFC with PCC in the right rectus gyrus. Left middle frontal gyrus exhibited increased rsFC. The PCC connectivity with the right rectus gyrus was found to be negatively correlated with the CIAS scores in the smokers with IGA before correction. Our results suggested that smokers with IGA had functional changes in brain areas related to motivation and executive function compared with the nonsmokers with IGA. Hindawi Publishing Corporation 2014 2014-11-18 /pmc/articles/PMC4255056/ /pubmed/25506057 http://dx.doi.org/10.1155/2014/825787 Text en Copyright © 2014 Xue Chen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chen, Xue
Wang, Yao
Zhou, Yan
Sun, Yawen
Ding, Weina
Zhuang, Zhiguo
Xu, Jianrong
Du, Yasong
Different Resting-State Functional Connectivity Alterations in Smokers and Nonsmokers with Internet Gaming Addiction
title Different Resting-State Functional Connectivity Alterations in Smokers and Nonsmokers with Internet Gaming Addiction
title_full Different Resting-State Functional Connectivity Alterations in Smokers and Nonsmokers with Internet Gaming Addiction
title_fullStr Different Resting-State Functional Connectivity Alterations in Smokers and Nonsmokers with Internet Gaming Addiction
title_full_unstemmed Different Resting-State Functional Connectivity Alterations in Smokers and Nonsmokers with Internet Gaming Addiction
title_short Different Resting-State Functional Connectivity Alterations in Smokers and Nonsmokers with Internet Gaming Addiction
title_sort different resting-state functional connectivity alterations in smokers and nonsmokers with internet gaming addiction
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255056/
https://www.ncbi.nlm.nih.gov/pubmed/25506057
http://dx.doi.org/10.1155/2014/825787
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