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Quantitative correlation between transcriptional levels of ER chaperone, peroximal protein and FVIII productivity in human Hek-293 cell line

Hek-293 cell line presents good production platform for recombinant therapeutic proteins, however little is known about the components that contribute to the cellular control of recombinant protein production. In this study, we generated a Hek-293 producing recombinant factor VIII (FVIII) and we eva...

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Detalles Bibliográficos
Autores principales:	Rodrigues, Evandra Strazza, Picanço-Castro, Virgínia, Espanhol, Marta Regina, de Andrade, Luiz Alberto Martins, Palma, Patricia Vianna Bonini, Kashima, Simone, Fontes, Aparecida Maria, Covas, Dimas Tadeu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255388/ https://www.ncbi.nlm.nih.gov/pubmed/25530931 http://dx.doi.org/10.1186/2193-1801-2-328

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