DPP-4 inhibitor linagliptin ameliorates cardiovascular injury in salt-sensitive hypertensive rats independently of blood glucose and blood pressure

BACKGROUND: It remains to be elucidated whether dipeptidylpeptidase-4 (DPP-4) inhibitor can ameliorate cardiovascular injury in salt-sensitive hypertension. The present study was undertaken to test our hypothesis that linagliptin, a DPP-4 inhibitor, administration initiated after onset of hypertensi...

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Detalles Bibliográficos
Autores principales: Koibuchi, Nobutaka, Hasegawa, Yu, Katayama, Tetsuji, Toyama, Kensuke, Uekawa, Ken, Sueta, Daisuke, Kusaka, Hiroaki, Ma, MingJie, Nakagawa, Takashi, Lin, Bowen, Kim-Mitsuyama, Shokei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255443/
https://www.ncbi.nlm.nih.gov/pubmed/25471116
http://dx.doi.org/10.1186/s12933-014-0157-0

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