Comprehensive analysis of microRNA-regulated protein interaction network reveals the tumor suppressive role of microRNA-149 in human hepatocellular carcinoma via targeting AKT-mTOR pathway

BACKGROUND: Our previous study identified AKT1, AKT2 and AKT3 as unfavorable prognostic factors for patients with hepatocellular carcinoma (HCC). However, limited data are available on their exact mechanisms in HCC. Since microRNAs (miRNAs) are implicated in various human cancers including HCC, we a...

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Detalles Bibliográficos
Autores principales: Zhang, Yanqiong, Guo, Xiaodong, Xiong, Lu, Yu, Lingxiang, Li, Zhiwei, Guo, Qiuyan, Li, Zhiyan, Li, Boan, Lin, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255446/
https://www.ncbi.nlm.nih.gov/pubmed/25424347
http://dx.doi.org/10.1186/1476-4598-13-253

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