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Structural Basis for Membrane Targeting of the BBSome by ARL6
The BBSome is a coat-like ciliary trafficking complex composed of proteins mutated in Bardet-Biedl syndrome (BBS). A critical step in BBSome-mediated sorting is recruitment of the BBSome to membranes by the GTP–bound Arf-like GTPase ARL6. We have determined crystal structures of C. reinhardtii ARL6–...
Autores principales: | Mourão, André, Nager, Andrew R., Nachury, Maxence V., Lorentzen, Esben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255524/ https://www.ncbi.nlm.nih.gov/pubmed/25402481 http://dx.doi.org/10.1038/nsmb.2920 |
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