PLD3 is accumulated on neuritic plaques in Alzheimer’s disease brains

INTRODUCTION: Recently, a whole-exome sequencing (WES) study showed that a rare variant rs145999145 composed of p.Val232Met located in exon 7 of the phospholipase D3 (PLD3) gene confers a doubled risk for late-onset Alzheimer’s disease (AD). Knockdown of PLD3 elevates the levels of extracellular amy...

Descripción completa

Detalles Bibliográficos
Autores principales: Satoh, Jun-ichi, Kino, Yoshihiro, Yamamoto, Yoji, Kawana, Natsuki, Ishida, Tsuyoshi, Saito, Yuko, Arima, Kunimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255636/
https://www.ncbi.nlm.nih.gov/pubmed/25478031
http://dx.doi.org/10.1186/s13195-014-0070-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255636/
https://www.ncbi.nlm.nih.gov/pubmed/25478031
http://dx.doi.org/10.1186/s13195-014-0070-5

Ejemplares similares