Cargando…

Distinct Properties of the Two Isoforms of CDP-Diacylglycerol Synthase

[Image: see text] CDP-diacylglycerol synthases (CDS) are critical enzymes that catalyze the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA). Here we show in vitro that the two isoforms of human CDS, CDS1 and CDS2, show different acyl chain specificities for its lipid substrate....

Descripción completa

Detalles Bibliográficos
Autores principales:	D’Souza, Kenneth, Kim, Yeun Ju, Balla, Tamas, Epand, Richard M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255645/ https://www.ncbi.nlm.nih.gov/pubmed/25375833 http://dx.doi.org/10.1021/bi501250m

Ejemplares similares

AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway
por: Mak, Hoi Yin, et al.
Publicado: (2021)

Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1
por: Blunsom, Nicholas J., et al.
Publicado: (2018)

CDP-Diacylglycerol Synthases (CDS): Gateway to Phosphatidylinositol and Cardiolipin Synthesis
por: Blunsom, Nicholas J., et al.
Publicado: (2020)

Antidepressant stimulation of CDP-diacylglycerol synthesis does not require monoamine reuptake inhibition
por: Aboukhatwa, Marwa A, et al.
Publicado: (2010)

Diacylglycerol Kinase-ε: Properties and Biological Roles
por: Epand, Richard M., et al.
Publicado: (2016)

CDP-Diacylglycerol Synthetase Coordinates Cell Growth and Fat Storage through Phosphatidylinositol Metabolism and the Insulin Pathway
por: Liu, Yuan, et al.
Publicado: (2014)

Diverse antidepressants increase CDP-diacylglycerol production and phosphatidylinositide resynthesis in depression-relevant regions of the rat brain
por: Tyeryar, Kimberly R, et al.
Publicado: (2008)

Phylogenetic analysis of the diacylglycerol kinase family of proteins and identification of multiple highly-specific conserved inserts and deletions within the catalytic domain that are distinctive characteristics of different classes of DGK homologs
por: Gupta, Radhey S., et al.
Publicado: (2017)

Sustained phospholipase C stimulation of H9c2 cardiomyoblasts by vasopressin induces an increase in CDP-diacylglycerol synthase 1 (CDS1) through protein kinase C and cFos
por: Blunsom, Nicholas J., et al.
Publicado: (2019)

Reduced expression of CDP-DAG synthase changes lipid composition and leads to male sterility in Drosophila
por: Laurinyecz, Barbara, et al.
Publicado: (2016)

Status report of the HARP-CDP group
por: Bolshakova, A, et al.
Publicado: (2007)

Differential regulation of diacylglycerol kinase isoform in human failing hearts
por: Bilim, Olga, et al.
Publicado: (2011)

2008 Status Report of the HARP-CDP group
por: Bolshakova, A, et al.
Publicado: (2008)

Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function
por: He, Yue, et al.
Publicado: (2014)

Crystal structures of phosphatidyl serine synthase PSS reveal the catalytic mechanism of CDP-DAG alcohol O-phosphatidyl transferases
por: Centola, Martin, et al.
Publicado: (2021)

Structural basis for catalysis in a CDP-alcohol phosphotransferase
por: Sciara, Giuliano, et al.
Publicado: (2014)

Effect of cdp-choline on microcirculatory alterations during endotoxemia
por: Schmidt, K, et al.
Publicado: (2013)

The essential roles of cytidine diphosphate‐diacylglycerol synthase in bloodstream form Trypanosoma brucei
por: Lilley, Alison C., et al.
Publicado: (2014)

Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase‐related protein via different regions
por: Furuta, Masataka, et al.
Publicado: (2023)

Nitric oxide synthase isoforms play distinct roles during acute peritonitis
por: Ni, Jie, et al.
Publicado: (2010)

Three Distinct Isoforms of ATP Synthase Subunit c Are Expressed in T. brucei and Assembled into the Mitochondrial ATP Synthase Complex
por: Gulde, Paul E., et al.
Publicado: (2013)

Sphingomyelin synthase-related protein generates diacylglycerol via the hydrolysis of glycerophospholipids in the absence of ceramide
por: Murakami, Chiaki, et al.
Publicado: (2021)

Diacylglycerol-evoked activation of PKC and PKD isoforms in regulation of glucose and lipid metabolism: a review
por: Kolczynska, Katarzyna, et al.
Publicado: (2020)

CDP++.Italian: Modelling Sublexical and Supralexical Inconsistency in a Shallow Orthography
por: Perry, Conrad, et al.
Publicado: (2014)

Reply to 'Corrections to the HARP-CDP Analysis of the LSND Neutrino Oscillation Backgrounds'
por: Bolshakova, A., et al.
Publicado: (2011)

HARP-CDP hadroproduction data: Comparison with FLUKA and GEANT4 simulations
por: Bolshakova, A., et al.
Publicado: (2010)

Cytidinediphosphate diacylglycerol synthase—Mediated phosphatidic acid metabolism is crucial for early embryonic development of Arabidopsis
por: Du, Xin-Qiao, et al.
Publicado: (2022)

Distinct functional properties of two electrogenic isoforms of the SLC34 Na‐Pi cotransporter
por: Mizutani, Natsuki, et al.
Publicado: (2019)

Distinct Calcium Binding and Structural Properties of Two Centrin Isoforms from Toxoplasma gondii
por: Bombardi, Luca, et al.
Publicado: (2020)

Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse
por: Gharbi, Severine I., et al.
Publicado: (2011)

Friedelin in Maytenus ilicifolia Is Produced by Friedelin Synthase Isoforms
por: Alves, Thaís B., et al.
Publicado: (2018)

mRNA expression of diacylglycerol kinase isoforms in insulin-sensitive tissues: effects of obesity and insulin resistance
por: Mannerås-Holm, Louise, et al.
Publicado: (2015)

Targeting nanomedicines in the treatment of Crohn’s disease: focus on certolizumab pegol (CDP870)
por: Dinesen, Lotte, et al.
Publicado: (2007)

Luminescence at the axial centers of CdP(2)-D(4)(8) crystals
por: Beril, S.I., et al.
Publicado: (2018)

Indole C6 Functionalization of Tryprostatin B Using Prenyltransferase CdpNPT
por: Gardner, Eric D., et al.
Publicado: (2020)

Consensus Development Project (CDP): An overview of staffing for safe and effective nursing care
por: Ball, Jane E., et al.
Publicado: (2021)

Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation
por: St Germain, Michaela, et al.
Publicado: (2023)

CDP-choline to promote remyelination in multiple sclerosis: the need for a clinical trial
por: Gudi, Viktoria, et al.
Publicado: (2023)

Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study
por: Szentpetery, Zsofia, et al.
Publicado: (2009)

Engineering the Thermostability of the Mono- and Diacylglycerol Lipase SMG1 for the Synthesis of Diacylglycerols
por: Li, Lilang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qsk0i96ps55gbtch0fl0joo8df