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Triptolide reverses hypoxia-induced epithelial–mesenchymal transition and stem-like features in pancreatic cancer by NF-κB downregulation
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal malignancies characterized by an intense tumor stroma with hypoperfused regions, a significant inflammatory response and pronounced therapy resistance. New therapeutic agents are urgently needed. The plant-derived agent triptolide also...
Autores principales: | Liu, Li, Salnikov, Alexei V, Bauer, Nathalie, Aleksandrowicz, Ewa, Labsch, Sabrina, Nwaeburu, Clifford, Mattern, Jürgen, Gladkich, Jury, Schemmer, Peter, Werner, Jens, Herr, Ingrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255690/ https://www.ncbi.nlm.nih.gov/pubmed/24615157 http://dx.doi.org/10.1002/ijc.28583 |
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