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Protection of CpG islands against de novo DNA methylation during oogenesis is associated with the recognition site of E2f1 and E2f2

BACKGROUND: Epigenetic reprogramming during early mammalian embryonic and germ cell development is a genome-wide process. CpG islands (CGIs), central to the regulation of mammalian gene expression, are exceptional in terms of whether, when and how they are affected by epigenetic reprogramming. RESUL...

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Detalles Bibliográficos
Autores principales: Saadeh, Heba, Schulz, Reiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255709/
https://www.ncbi.nlm.nih.gov/pubmed/25478011
http://dx.doi.org/10.1186/1756-8935-7-26

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