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Dipeptidyl Peptidase IV as a Potential Target for Selective Prodrug Activation and Chemotherapeutic Action in Cancers
[Image: see text] The efficacy of chemotherapeutic drugs is often offset by severe side effects attributable to poor selectivity and toxicity to normal cells. Recently, the enzyme dipeptidyl peptidase IV (DPPIV) was considered as a potential target for the delivery of chemotherapeutic drugs. The pur...
Autores principales: | Dahan, Arik, Wolk, Omri, Yang, Peihua, Mittal, Sachin, Wu, Zhiqian, Landowski, Christopher P., Amidon, Gordon L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255727/ https://www.ncbi.nlm.nih.gov/pubmed/25365774 http://dx.doi.org/10.1021/mp500483v |
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